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KMID : 1031120160060020099
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Journal of Epilepsy Research
2016 Volume.6 No. 2 p.99 ~ p.101
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Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function
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Park Hyeon-Mi
Noh Young
Yang Ji-Won
Shin Dong-Hoon
Lee Yeong-Bae
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Abstract
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Cefepime-induced encephalopathy including nonconvulsive status epilepticus has been known to develop in the patients with renal impairment. However, we report a 74-year-old woman with normal renal function who developed stuporous mental status during cefepime administration. Electroencephalogram (EEG) revealed 2 Hz rhythmic sharp-and-waves continuously, which suggested nonconvulsive status epilepticus (NCSE). After cefepime discontinuation, clinical symptoms recovered gradually and EEG findings showed only background slowing without epileptiform discharges. Cefepime-induced NCSE could be developed even in the patients with normal renal function, when they are elderly. Therefore, clinicians should be aware of the possibility of cefepime-induced NCSE when prescribing cefepime even to the patients with normal renal function.
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KEYWORD
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Cefepime, EEG, Non-convulsive status epilepticus, Renal function
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